Phenyl isocyanate → HCID 18536729, 화합물

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[OH:1][CH2:2][C:3]1[N:4]=[CH:5][N:6]([C:8]2[CH:9]=[C:10]3[C:15](=[CH:16][C:17]=2[C:18]([F:21])([F:20])[F:19])[NH:14][C:13](=[O:22])[C:12]([C:23]([O:25][CH2:26][CH3:27])=[O:24])=[CH:11]3)[CH:7]=1.[C:28]1([N:34]=[C:35]=[O:36])[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1>>[O:22]=[C:13]1[C:12]([C:23]([O:25][CH2:26][CH3:27])=[O:24])=[CH:11][C:10]2[C:15](=[CH:16][C:17]([C:18]([F:20])([F:21])[F:19])=[C:8]([N:6]3[CH:7]=[C:3]([CH2:2][O:1][C:35](=[O:36])[NH:34][C:28]4[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=4)[N:4]=[CH:5]3)[CH:9]=2)[NH:14]1

참가 물질

반응물 2

HCID 7672Phenyl isocyanate

HCID 9951850HCID 9951850, 화합물

생성물 1

HCID 18536729HCID 18536729, 화합물수율 89.1%

실험 절차

Using the compound of Example 17 (200 mg, 525 μmol) and phenyl isocyanate (93.9 mg, 0.788 mmol), and through the process similar to Example 18, 234 mg of title compound were obtained as colorless powder. Yield 89%.

출처 및 근거

ORD 기록: ord-cc83d818fe8547c7aa37b69fe52d195d
출처 데이터셋: uspto-grants-2003_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06562839B1

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