(1,1'-Biphenyl)-4-sulfonic acid → (1,1'-Biphenyl)-4-sulphonyl chloride

HRID 412115

반응식

HRID 412115 반응식
[C:1]1([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[CH:6]=[CH:5][C:4]([S:7](O)(=[O:9])=[O:8])=[CH:3][CH:2]=1.P(Cl)(Cl)(Cl)(Cl)[Cl:18]>O>[C:1]1([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[CH:6]=[CH:5][C:4]([S:7]([Cl:18])(=[O:9])=[O:8])=[CH:3][CH:2]=1

참가 물질

4

반응물 2

HCID 16673(1,1'-Biphenyl)-4-sulfonic acidHCID 24819Phosphorus pentachloride

생성물 1

HCID 74192(1,1'-Biphenyl)-4-sulphonyl chloride

시약·촉매·용매 1

HCID 962Water용매

실험 절차

4-Biphenyl sulfonic acid (2.4 g, 10 mmol) was heated to 100 C with phosphorus pentachloride (2.1 g, 10 mmol) overnight. The reaction was cooled to RT, diluted with water, filtered and washed with water. The solid was then triturated with EtOAc-ether and the beige solid was used in the next reaction without further purification.

후처리

  1. filtrationfiltered
  2. washwashed with water
  3. customThe solid was then triturated with EtOAc-ether
  4. customthe beige solid was used in the next reaction without further purification

출처 및 근거

ORD 기록
ord-7f8661eeb564456787d1f3625db9a69e
출처 데이터셋
uspto-grants-2003_05
특허 번호
US06562842B2

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