1-(4-Cyano-3-fluorobenzyl)-5-imidazolecarboxaldehyde → 1-(4-Cyano-3,5-dichlorobenzyl)-5-imidazolecarboxaldehyde

반응식

[C:1]([C:3]1[C:10]([Cl:11])=[CH:9][C:6]([CH2:7]Br)=[CH:5][C:4]=1[Cl:12])#[N:2].C(C1C=CC(C[N:20]2[C:24]([CH:25]=[O:26])=[CH:23][N:22]=[CH:21]2)=CC=1F)#N>>[C:1]([C:3]1[C:10]([Cl:11])=[CH:9][C:6]([CH2:7][N:20]2[C:24]([CH:25]=[O:26])=[CH:23][N:22]=[CH:21]2)=[CH:5][C:4]=1[Cl:12])#[N:2]

참가 물질

반응물 2

HCID 114247081-(4-Cyano-3-fluorobenzyl)-5-imidazolecarboxaldehyde

HCID 185361844-(Bromomethyl)-2,6-dichlorobenzonitrile

생성물 1

HCID 185361351-(4-Cyano-3,5-dichlorobenzyl)-5-imidazolecarboxaldehyde

실험 절차

The titled product was prepared from the product of Step C using the same procedures as those described in Example 1, Steps D through G for the preparation of 1-(4-cyano-3-fluorobenzyl)-5-imidazolecarboxaldehyde.

출처 및 근거

ORD 기록: ord-6239268bec174954a251cbb5033719c8
출처 데이터셋: uspto-grants-2003_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06562823B1

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