Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Chlorobenzaldehyde → 2-m-Chlorophenyl-3-(3-trifluoromethyl-4-fluorophenyl)-5-ethyl oxazolidine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Chlorobenzaldehyde | HCID 11477 | — |
| 반응물 | 1-(3-Trifluoromethyl-4-fluorophenylamino)-2-butanol | HCID 20152671 | — |
| 촉매 | Methanesulfonic Acid | HCID 6395 | — |
| 생성물 | 2-m-Chlorophenyl-3-(3-trifluoromethyl-4-fluorophenyl)-5-ethyl oxazolidine | HCID 20152670 | — |
반응 단계
Meta-chlorobenzaldehyde (2.3 g, 0.016 mole) was combined with 5 g of 1-(3-trifluoromethyl-4-fluorophenylamino)-2-butanol and 3 drops of methane sulfonic acid was added. The mixture was heated on the steam bath for about one hour and stripped on the rotary evaporator. The product, a sticky, thick liquid, was characterized by IR and NMR.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04723986 |
| 출처 데이터셋 | uspto-grants-1988_02 |
| ORD ID | ord-2606b9cbf440416d8f3e63a1500dbed7 |
| 출처 메모 | uspto-grants-1988_02 |