Benzoyl Peroxide → 6-(Chloromethyl)quinoxaline

HRID 412671노트

반응식

HRID 412671 반응식
[CH3:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[N:8]=[CH:7][CH:6]=[N:5]2.[Cl:12]N1C(=O)CCC1=O.C(OOC(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1>C(#N)C>[Cl:12][CH2:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[N:8]=[CH:7][CH:6]=[N:5]2

참가 물질

5

반응물 3

HCID 7187Benzoyl Peroxide2회HCID 31398ChlorosuccinimideHCID 2425676-Methylquinoxaline

생성물 1

HCID 101251116-(Chloromethyl)quinoxaline

시약·촉매·용매 1

HCID 6342Acetonitrile용매

실험 절차

In a 500 ml flask, 6-methyl-quinoxaline (10 g, 69.4 mmol) was dissolved together with N-chlorosuccinimide (14 g, 105.3 mmol) and benzoyl peroxide (BP, 0.4 g, 1.65 mmol) in 240 g of acetonitrile. The flask was connected to a reflux-condenser and the solution was refluxed for 6 hours followed by another addition of 0.1 g of benzoyl peroxide. Reflux was then continued for another 6 hours.

후처리

  1. customThe flask was connected to a reflux-condenser
  2. temperaturethe solution was refluxed for 6 hours
  3. temperatureReflux

출처 및 근거

ORD 기록
ord-2ac37084b32c4c2fb37b8486e49005ec
출처 데이터셋
uspto-grants-2003_05
특허 번호
US06562972B1

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