Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Phosphate, Tribasic → 2,6,2'-Trimethyl-biphenyl
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Phosphate, Tribasic | HCID 62657 | — |
| 반응물 | 2-Bromo-m-xylene | HCID 68471 | — |
| 반응물 | 2-Methylphenyl boronic acid | HCID 2733267 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | 2,6,2'-Trimethyl-biphenyl | HCID 9813037 | 87% |
반응 단계
2-Bromo-m-xylene (186 mg, 1.01 mmol) reacted with 2-methylphenylboronic acid (164 mg, 1.21 mmol) using 2/4 mol % of Pd(dba)2/Ph5FcP(t-Bu)2 and K3PO4 (640 mg, 3.00 mmol) in toluene at 100° C. to give the title compound (170 mg, 87%) as a colorless oil: 1H-NMR (400 MHz, CDCl3): δ 7.31-7.25 (m, 3H), 7.20-7.11 (m, 3H), 7.03 (m, 1H), 1.98 (s, 3H), 1.96 (s, 6H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06562989B2 |
| 출처 데이터셋 | uspto-grants-2003_05 |
| ORD ID | ord-0ff99723968a4418be2450efd7a59780 |
| 출처 메모 | uspto-grants-2003_05 |