Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Triethylamine → Phenylphosphine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | Iodobenzene | HCID 11575 | — |
| 반응물 | Phosphine | HCID 24404 | — |
| 반응물 | Tri-o-tolylphosphine | HCID 80271 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 촉매 | palladium(II) acetate | HCID 167845 | — |
| 용매 | O-Xylene | HCID 7237 | — |
| 생성물 | Phenylphosphine | HCID 12519 | 9% |
| 생성물 | Diphenylphosphine | HCID 70017 | 7% |
반응 단계
A one liter xylene solution containing iodobenzene (375 g, 1.84 moles), triethylamine (150 g, 1.5 moles) and the palladium dimer (1:1 adduct of palladium(II) acetate and tri(o-tolyl)phosphine, 1.20 g, 1.2 mmole, 0.07 mole %) was charged to a one gallon autoclave under a nitrogen blanket. The solution was maintained at 500 psig phosphine pressure and 110° C., with stirring at 500 rpm, for 5 hours. At this time the autoclave was cooled to ambient temperature, vented and discharged as described above. Analysis of the xylene phase by GC/FID (with area percent integration) gave only monophenylphosphine (9%) and diphenylphosphine (7%), with no sign of triphenyl-phosphine, for a total conversion of iodobenzene of approximately 16%.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06563005B1 |
| 출처 데이터셋 | uspto-grants-2003_05 |
| ORD ID | ord-56768d8b3dc6459d9590b91c2a5eadbe |
| 출처 메모 | uspto-grants-2003_05 |