3,3-Dimethoxy-4-benzyloxycarbonylamino-tetrahydrofuran → 3,3-Dimethoxy4-amino-tetrahydrofuran

HRID 413231노트

반응식

HRID 413231 반응식
[CH3:1][O:2][C:3]1([O:19][CH3:20])[CH:7]([NH:8]C(OCC2C=CC=CC=2)=O)[CH2:6][O:5][CH2:4]1>[Pd].C(O)C>[CH3:1][O:2][C:3]1([O:19][CH3:20])[CH:7]([NH2:8])[CH2:6][O:5][CH2:4]1

참가 물질

4

반응물 1

HCID 185234863,3-Dimethoxy-4-benzyloxycarbonylamino-tetrahydrofuran

생성물 1

HCID 185234873,3-Dimethoxy4-amino-tetrahydrofuran

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 702Ethanol용매

실험 절차

A mixture of 3,3-Dimethoxy4-benzyloxycarbonylamino-tetrahydrofuran (16 g, 57 mmol) and 10% palladium on charcoal (2 g) in ethanol (200 ml) was stirred under an atmosphere of hydrogen (50 psi) for 12 h. The mixture was filtered and concentrated to afford the title compound as a yellow oil, 8 g, 100%.

후처리

  1. filtrationThe mixture was filtered
  2. concentrationconcentrated

출처 및 근거

ORD 기록
ord-ddca4aa2d4c2416d9a5c942fdeeb5746
출처 데이터셋
uspto-grants-2003_05
특허 번호
US06566373B2

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