Ethyl 4-sulfanylbutanoate → Ethyl 4-(4-(4-ethoxyphenyl)-2-formylphenylthio)butyrate

HRID 413589노트

반응식

HRID 413589 반응식
[CH2:1]([O:3][C:4]1[CH:9]=[CH:8][C:7]([C:10]2[CH:11]=[CH:12][C:13](F)=[C:14]([CH:17]=2)[CH:15]=[O:16])=[CH:6][CH:5]=1)[CH3:2].[SH:19][CH2:20][CH2:21][CH2:22][C:23]([O:25][CH2:26][CH3:27])=[O:24]>>[CH2:1]([O:3][C:4]1[CH:9]=[CH:8][C:7]([C:10]2[CH:11]=[CH:12][C:13]([S:19][CH2:20][CH2:21][CH2:22][C:23]([O:25][CH2:26][CH3:27])=[O:24])=[C:14]([CH:15]=[O:16])[CH:17]=2)=[CH:6][CH:5]=1)[CH3:2]

참가 물질

3

반응물 2

HCID 271824Ethyl 4-sulfanylbutanoateHCID 185333825-(4-Ethoxyphenyl)-2-fluorobenzaldehyde

생성물 1

HCID 18533388Ethyl 4-(4-(4-ethoxyphenyl)-2-formylphenylthio)butyrate수율 73%

실험 절차

Ethyl 4-(4-(4-ethoxyphenyl)-2-formylphenylthio)butyrate was synthesized from 5-(4-ethoxyphenyl)-2-fluorobenzaldehyde and ethyl 4-mercaptobutyrate in the same manner as Example 2. After concentration of an extracted solution, crystallization from hexane/isopropyl ether yielded ethyl 4-(4-(4-ethoxyphenyl)-2-formylphenylthio)butyrate (Yield 73%) as yellow crystals.

후처리

  1. customAfter concentration of an extracted solution, crystallization from hexane/isopropyl ether

출처 및 근거

ORD 기록
ord-32e63a7f124c4f658a4bcbd6aa55376c
출처 데이터셋
uspto-grants-2003_05
특허 번호
US06566535B1

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