Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 3-(4-Trifluoromethylphenylthio)propanal
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Acrolein | HCID 7847 | — |
| 반응물 | 4-(Trifluoromethyl)thiophenol | HCID 136653 | — |
| 촉매 | Triethylamine | HCID 8471 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 3-(4-Trifluoromethylphenylthio)propanal | HCID 14347982 | 99.6% |
반응 단계
Ten grams of 4-trifluoromethylthiophenol was dissolved in 15 ml of THF, and after adding 4.0 g of 95% acrolein under ice-cooling, 0.1 g of triethylamine was added while thoroughly stirring the reaction solution. After stirring for 1.5 hours under ice-cooling, the reaction solution was poured into water and extracted with ether. The ether layer was washed with water and dried over anhydrous magnesium sulfate. The solvent was removed under reduced pressure to obtain 13.1 g of 3-(4-trifluoromethylphenylthio)propionaldehyde.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04789396 |
| 출처 데이터셋 | uspto-grants-1988_12 |
| ORD ID | ord-8fffb9f5120448a293a9012ddff4bfe1 |
| 출처 메모 | uspto-grants-1988_12 |