Diethyl (2-hydroxyethyl)phosphonate → Diethyl 2-[[5-(o-chloro-p-trifluoromethyl-phenoxy)-2-nitrophenoxy]acetoxy]-ethylphosphonate

HRID 414650노트

반응식

HRID 414650 반응식
[Cl:1][C:2]1[CH:22]=[C:21]([C:23]([F:26])([F:25])[F:24])[CH:20]=[CH:19][C:3]=1[O:4][C:5]1[CH:6]=[CH:7][C:8]([N+:16]([O-:18])=[O:17])=[C:9]([CH:15]=1)[O:10][CH2:11][C:12](Cl)=[O:13].[OH:27][CH2:28][CH2:29][P:30](=[O:37])([O:34][CH2:35][CH3:36])[O:31][CH2:32][CH3:33]>>[Cl:1][C:2]1[CH:22]=[C:21]([C:23]([F:26])([F:25])[F:24])[CH:20]=[CH:19][C:3]=1[O:4][C:5]1[CH:6]=[CH:7][C:8]([N+:16]([O-:18])=[O:17])=[C:9]([CH:15]=1)[O:10][CH2:11][C:12]([O:27][CH2:28][CH2:29][P:30](=[O:37])([O:31][CH2:32][CH3:33])[O:34][CH2:35][CH3:36])=[O:13]

참가 물질

3

반응물 2

HCID 312225Diethyl (2-hydroxyethyl)phosphonateHCID 212815435-(o-Chloro-p-trifluoromethyl-phenoxy)-2-nitrophenoxy-acetyl chloride

생성물 1

HCID 21281502Diethyl 2-[[5-(o-chloro-p-trifluoromethyl-phenoxy)-2-nitrophenoxy]acetoxy]-ethylphosphonate

실험 절차

by using 5-(o-chloro-p-trifluoromethyl-phenoxy)-2-nitrophenoxy-acetyl chloride and diethyl 2-hydroxyethylphosphonate there is obtained diethyl 2-[[5-(o-chloro-p-trifluoromethyl-phenoxy)-2-nitrophenoxy]acetoxy]-ethylphosphonate, 1H-NMR (CDCl3, 400 MHz) 7.96 ppm (d, 1H), 7.80 ppm (d, 1H), 7.59 ppm (q, 1H), 7.21 ppm (d, 1H), 6.71 ppm (d, 1H), 6.52 ppm (q, 1H), 4.78 ppm (s, 2H), 4.45 ppm (m, 2H), 4.12 ppm (m, 4H), 2.17 ppm (m, 2H), 1.33 ppm (tt, 6H);

출처 및 근거

ORD 기록
ord-d68d410ad66a4f1d89df103b9b2d45cc
출처 데이터셋
uspto-grants-1988_12
특허 번호
US04792616

반응 노트

불러오는 중…