Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-Methylol-alpha-chloroacetamide → 4-Methyl-6-alpha-chloroacetylaminomethyl-7-hydroxy-1-indanone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-Methylol-alpha-chloroacetamide | HCID 62466 | — |
| 반응물 | 7-Hydroxy-4-methyl-1-indanone | HCID 12436244 | — |
| 용매 | Sulfuric Acid | HCID 1118 | — |
| 생성물 | 4-Methyl-6-alpha-chloroacetylaminomethyl-7-hydroxy-1-indanone | HCID 13604141 | — |
반응 단계
9.3 Grams of 4-methyl-7-hydroxy-1-indanone and 30 g of N-hydroxymethyl-α-chloroacetamide were dissolved by adding 280 ml of concentrated sulfuric acid under a cooling condition. After the mixture was allowed to stand overnight, the mixture was poured into ice-water. The crystals formed in the mixture were collected by filtration and were recrystallized from ethanol to obtain 49 g of 4-methyl-6-α-chloroacetylaminomethyl-7-hydroxy-1-indanone.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04792628 |
| 출처 데이터셋 | uspto-grants-1988_12 |
| ORD ID | ord-4a7e1f9656b248dd9a61a3d930cddd9f |
| 출처 메모 | uspto-grants-1988_12 |