Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Methyl-6-nitro-7-hydroxy-1-indanone → 6-Amino-4-methyl-7-hydroxy-1-indanone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Methyl-6-nitro-7-hydroxy-1-indanone | HCID 13604142 | — |
| 촉매 | HCID 178418390 | HCID 178418390 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 6-Amino-4-methyl-7-hydroxy-1-indanone | HCID 13604143 | 77.8% |
반응 단계
Into a solution of 26.0 g of 4-methyl-6-nitro-7-hydroxy-1-indanone in 50 ml of dimethylformamide was added 2.6 g of 10% palladium carbon, then the mixture was subjected to a catalytic hydrogenation under an atmospheric pressure at 0° C. to a room temperature. The catalyst was removed by filtration and the solvent was removed by evaporation to obtain 17.3 g of 6-amino-4-methyl-7-hydroxy-1-indanone.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04792628 |
| 출처 데이터셋 | uspto-grants-1988_12 |
| ORD ID | ord-a44c2083e6a84f01b2f3cd0be27a7c8b |
| 출처 메모 | uspto-grants-1988_12 |