돌아가기
Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 415003생성일: 2026년 10월 25일

2-Methyl-5-(2-methyl-4-nitrophenoxy)pyridine → 3-Methyl-4-((6-methylpyridin-3-yl)oxy)aniline

https://huagongshe.com/reaction/415003

반응식

참여 물질

역할이름HCID투입량
반응물2-Methyl-5-(2-methyl-4-nitrophenoxy)pyridineHCID 17990102—
반응물HCID 178418361HCID 178418361—
촉매PalladiumHCID 23938—
용매MethanolHCID 887—
생성물3-Methyl-4-((6-methylpyridin-3-yl)oxy)anilineHCID 1142443487.2%

반응 단계

A mixture of 2-methyl-5-(2-methyl-4-nitro-phenoxy)-pyridine (11.5 g, 47.1 mmol) and palladium on carbon (300 mg, 10 wt. %, wet) in MeOH (200 mL) was flashed with hydrogen. A hydrogen balloon was then applied to the reaction mixture. The reaction was stirred for 2 hours and the solution was filtered through a pad of celite, and the pad was washed with MeOH (300 mL). Concentration of the solution gave crude product (8.8 g, 87%) as light yellow solid.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08088766B2
출처 데이터셋uspto-grants-2012_01
ORD IDord-9194d436cccf4778be18741d4c66f30f
출처 메모uspto-grants-2012_01