Acetonitrile → 6-Chloro-2-fluoro-3-methoxybenzamide

HRID 415577노트

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HRID 415577 반응식
[Cl:1][C:2]1[C:7]([C:8](O)=[O:9])=[C:6]([F:11])[C:5]([O:12][CH3:13])=[CH:4][CH:3]=1.CC#[N:16]>>[Cl:1][C:2]1[C:7]([C:8]([NH2:16])=[O:9])=[C:6]([F:11])[C:5]([O:12][CH3:13])=[CH:4][CH:3]=1

참가 물질

3

반응물 2

HCID 6342AcetonitrileHCID 38560396-Chloro-2-fluoro-3-methoxybenzoic acid

생성물 1

HCID 179993606-Chloro-2-fluoro-3-methoxybenzamide수율 85%

실험 절차

Synthesised from commercially available 6-chloro-2-fluoro-3-methoxybenzenecarboxylic acid according to Method A, scheme 1. Yield 85%, mp 154-156° C., HPLC-MS (method 1): m/z 245 [M+H+CH3CN]+, Rt=2.37 min.

출처 및 근거

ORD 기록
ord-08d1a11d2190433f8041b03d146c33d7
출처 데이터셋
uspto-grants-2012_01
특허 번호
US08088791B2

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