4-(Trifluoromethyl)phenylboronic acid → 5-Acetyl-2-[4-(trifluoromethyl)phenyl]furan

HRID 416039노트

반응식

HRID 416039 반응식
[F:1][C:2]([F:13])([F:12])[C:3]1[CH:8]=[CH:7][C:6](B(O)O)=[CH:5][CH:4]=1.Br[C:15]1[O:19][C:18]([C:20](=[O:22])[CH3:21])=[CH:17][CH:16]=1>>[F:1][C:2]([F:13])([F:12])[C:3]1[CH:8]=[CH:7][C:6]([C:15]2[O:19][C:18]([C:20](=[O:22])[CH3:21])=[CH:17][CH:16]=2)=[CH:5][CH:4]=1

참가 물질

3

반응물 2

HCID 27343894-(Trifluoromethyl)phenylboronic acidHCID 110305851-(5-Bromofuran-2-yl)ethan-1-one

생성물 1

HCID 591803155-Acetyl-2-[4-(trifluoromethyl)phenyl]furan

실험 절차

1-(5-(4-(Trifluoromethyl)phenyl)fur-2-yl)ethanone is prepared from 4-trifluoromethylbenzeneboronic acid and 5-bromo-2-acetylfuran according to general procedure A.

출처 및 근거

ORD 기록
ord-09f34556f48b4f6e9cdb90b1f2b70c40
출처 데이터셋
uspto-grants-2012_01
특허 번호
US08088819B2

반응 노트

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