참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Bromoacetic Acid | HCID 6227 | — |
| 반응물 | Potassium Hydroxide | HCID 14797 | — |
| 반응물 | HCID 178418558 | HCID 178418558 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | HCID 178418509 | HCID 178418509 | 86.6% |
반응 단계
In 200 ml of water were dissolved 15.0 g of 2,5-dimercapto-1,3,4-thiadiazole and 69 g of potassium hydroxide, and a solution of 13.9 g of bromoacetic acid in 30 ml of water was added thereto dropwise at room temperature. After the addition, the mixture was stirred at 60° C. for 1 hour, followed by allowing to cool to room temperature. The precipitated crystals were filtered and washed with water to obtain 18 g of the desired compound. Melting point: 161°-167° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04724199 |
|---|
| 출처 데이터셋 | uspto-grants-1988_02 |
|---|
| ORD ID | ord-03c19910184945d28d0037efcffa7194 |
|---|
| 출처 메모 | uspto-grants-1988_02 |
|---|
