Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-(4-Methylpiperazin-1-yl)benzaldehyde → HCID 178480647, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-(4-Methylpiperazin-1-yl)benzaldehyde | HCID 736533 | — |
| 반응물 | Tert-butyl malonate | HCID 21883978 | — |
| 반응물 | Sodium t-butoxide | HCID 23676156 | — |
| 반응물 | 1-Isocyano-2-methylpropan-2-yl methyl carbonate | HCID 25267464 | — |
| 반응물 | HCID 178507353 | HCID 178507353 | — |
| 용매 | Dichloromethane methanol | HCID 21226129 | — |
| 생성물 | HCID 178480647 | HCID 178480647 | — |
반응 단계
The compound was synthesized starting from 1H-benzo[d]imidazol-5-amine (0.85 mg, 6.37 mmol), 4-(4-methylpiperazin-1-yl)benzaldehyde (1.3 g, 6.37 mmol), mono-tert-butyl malonate (1.53 g, 9.55 mmol), 1-isocyano-2-methylpropan-2-yl methyl carbonate (1.1 g, 7.01 mmol) in MeOH/CH2Cl2 1:1 (30 ml) with stirring for 2.5 days and sodium tert.-butoxide (0.235 g, 2.10 mmol) according to method 5.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08530670B2 |
| 출처 데이터셋 | uspto-grants-2013_09 |
| ORD ID | ord-6cfc93dfe97b44509fdf6828efbfefa2 |
| 출처 메모 | uspto-grants-2013_09 |