Dimethylamine → HCID 178482966, 화합물

HRID 41777

반응식

HRID 41777 반응식
[NH:1]1[C:5]2[CH:6]=[CH:7][C:8]([N:10]3[CH:14]([C:15]4[CH:20]=[CH:19][C:18]([N:21]5[CH2:26][CH2:25][O:24][CH2:23][CH2:22]5)=[CH:17][CH:16]=4)[C:13](O)=[CH:12][C:11]3=[O:28])=[CH:9][C:4]=2[N:3]=[CH:2]1.[CH3:29][NH:30][CH3:31]>C1COCC1.C1(C)C=CC=CC=1.CN(C=O)C>[NH:1]1[C:5]2[CH:6]=[CH:7][C:8]([N:10]3[CH:14]([C:15]4[CH:20]=[CH:19][C:18]([N:21]5[CH2:22][CH2:23][O:24][CH2:25][CH2:26]5)=[CH:17][CH:16]=4)[C:13]([N:30]([CH3:31])[CH3:29])=[CH:12][C:11]3=[O:28])=[CH:9][C:4]=2[N:3]=[CH:2]1

참가 물질

5

반응물 2

HCID 674DimethylamineHCID 178516575HCID 178516575, 화합물

생성물 1

HCID 178482966HCID 178482966, 화합물

시약·촉매·용매 2

HCID 8028Tetrahydrofuran용매HCID 21735183Dimethylformamide toluene용매

실험 절차

The compound was synthesized starting from 1-(1H-benzo[d]imidazol-5-yl)-4-hydroxy-5-(4-morpholinophenyl)-1H-pyrrol-2(5H)-one (1.0 g, 2.65 mmol) and a saturated solution of dimethylamine in THF (13 ml) in toluene/DMF (2:1; 15 ml) according to method 8b described above.

후처리

  1. customThe compound was synthesized

출처 및 근거

ORD 기록
ord-5d51770deaef48ad86b760740e6b4ffc
출처 데이터셋
uspto-grants-2013_09
특허 번호
US08530670B2

연결된 노트

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