4-Hydroxybenzaldehyde → 4-(12-Bromododecyloxy)benzaldehyde

HRID 417774

반응식

HRID 417774 반응식
[CH2:1]([O:11][C:12]1[CH:21]=[CH:20][C:15]([C:16]([O:18]C)=O)=[CH:14][CH:13]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10].C([O-])([O-])=O.[K+].[K+].OC1C=CC(C=O)=CC=1.[Br:37][CH2:38][CH2:39]CCCCCCCC(Br)CC>>[Br:37][CH2:38][CH2:39][CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2][CH2:1][O:11][C:12]1[CH:13]=[CH:14][C:15]([CH:16]=[O:18])=[CH:20][CH:21]=1

참가 물질

5

반응물 4

HCID 1264-HydroxybenzaldehydeHCID 11430Potassium CarbonateHCID 3574987Methyl 4-(decyloxy)benzoateHCID 218379191,10-Dibromododecane

생성물 1

HCID 866519174-(12-Bromododecyloxy)benzaldehyde

실험 절차

Synthesized as described above for compound 1. Quantities: K2CO3 (4.6 g, 33 mmol), p-hydroxybenzaldehye (3.27 g, 27 mmol), 1,10-dibromododecane (11.56 g, 35 mmol). Yield 7.0 g (70%). 1H NMR: δH (CDCl3; 300 MHz): 1.24-1.52 (16 H, m, CH2), 1.84 (4 H, m, O—CH2—CH2/Br—CH2—CH2), 3.40 (2 H, t, 3J=6.9 Hz, Br—CH2), 4.06 (2 H, t, 3J=6.5 Hz, O—CH2), 6.98 (2 H, d, 3J=8.7 Hz, Ar—H), 7.82 (2 H, d, 3J=8.8 Hz, Ar—H), 9.88 (1 H, s, COH). 13C NMR: δC (CDCl3; 75 MHz): 26.3, 28.6, 29.1, 29.4, 29.7, 29.8, 29.9, 33.2, 34.4, 68.8, 115.1, 130.1, 132.3, 164.6, 191.1.

후처리

  1. customSynthesized

출처 및 근거

ORD 기록
ord-b9412cffeaac409a947adc74a7b3fab1
출처 데이터셋
uspto-grants-2012_01
특허 번호
US08092712B2

연결된 노트

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