Borane;tetrahydrofuran → 7-Nitro-3,4-dihydro-2H-1,4-benzoxazine

참여 물질

역할	이름	HCID	투입량
반응물	Borane;tetrahydrofuran	HCID 2723981	—
반응물	7-nitro-3,4-dihydro-2H-1,4-benzoxazin-3-one	HCID 2763830	—
용매	Tetrahydrofuran	HCID 8028	—
생성물	7-Nitro-3,4-dihydro-2H-1,4-benzoxazine	HCID 18416151	83%

반응 단계

Using 7-nitro-4H-benzo[1,4]oxazin-3-one (2.9 g, 15 mmol) and borane-THF (45 ml of a 1M solution in THF, 45 mmol) in THF (40 mL) to yield the title compound as an orange solid (2.2 g, 83%). δH (CDCl3) 3.48-3.60 (2H, m), 4.20-4.32 (2H, m), 6.52 (1H, d, J 8.9 Hz), 7.69 (1H, d, J 2.4 Hz), 7.74 (1H, dd, J 8.9, 2.4 Hz). LCMS (ES+) 181 (M+H)+.

출처 및 근거

DOI	10.6084/m9.figshare.5104873.v1
특허 번호	US08093238B2
출처 데이터셋	uspto-grants-2012_01
ORD ID	ord-9ee9945552e24d7db4f27dd8f97f5c81
출처 메모	uspto-grants-2012_01