참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 2,5-Dimethyl-1H-indole | HCID 70965 | — |
| 반응물 | 4-Chloro-8-methylquinoline | HCID 12326335 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 용매 | N-methyl-2-pyrrolidone | HCID 13387 | — |
| 생성물 | 8-Methyl-(2,5-dimethyl-1H-indol-3-yl)quinoline | HCID 18729479 | 99.7% |
반응 단계
2,5-Dimethylindole (290 mg) and 8-methyl-4-chloroquinoline (360 mg) were suspended in N-methylpyrolidinone (0.5 ml), and maintained under a nitrogen atmosphere. The reaction was heated to 140° C. with stirring for 45 minutes. On cooling a deep red precipitate formed, the mixture was diluted with diethylether and the solid collected by filtration, and dried to give the sub-title compound (570 mg).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08093278B2 |
|---|
| 출처 데이터셋 | uspto-grants-2012_01 |
|---|
| ORD ID | ord-ae91cbb6e53f482bb788d4d9733ac7db |
|---|
| 출처 메모 | uspto-grants-2012_01 |
|---|
