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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 418575생성일: 2026년 10월 26일

3-Fluoro-4-(2-(1-methyl-1H-imidazol-2-yl)thieno[3,2-b]pyridin-7-yloxy)benzenamine → 4-(2-(1-Ethyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)-3-fluorobenzenamine

https://huagongshe.com/reaction/418575

반응식

참여 물질

역할이름HCID투입량
반응물3-Fluoro-4-(2-(1-methyl-1H-imidazol-2-yl)thieno[3,2-b]pyridin-7-yloxy)benzenamineHCID 59424480—
반응물2-(1-Ethyl-1H-imidazol-4-yl)-7-(2-fluoro-4-nitrophenoxy)thieno[3,2-b]pyridineHCID 66649032—
생성물4-(2-(1-Ethyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)-3-fluorobenzenamineHCID 59424455—

반응 단계

Following the procedure described for compound 9 (example 2, step 5) but substituting nitro compound 8 for the compound 14, title compound 15 was obtained as a yellow solid (86% yield). MS (m/z): 402.1 (M+H).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08093264B2
출처 데이터셋uspto-grants-2012_01
ORD IDord-21c8a82752b74a4593d4aec4d633adda
출처 메모uspto-grants-2012_01