2,4-Difluoro-1-iodobenzene → 1-(2,4-Difluorophenyl)-6-methyl-1H-indazol-4-amine

HRID 418771

반응식

HRID 418771 반응식
NC1C=CC=C2C=1C=NN2C1C=C(C=CC=1)C(OC)=O.[CH3:21][C:22]1[CH:23]=[C:24]([NH2:31])[C:25]2[CH:26]=[N:27][NH:28][C:29]=2[CH:30]=1.[F:32][C:33]1[CH:38]=[C:37]([F:39])[CH:36]=[CH:35][C:34]=1I>>[F:32][C:33]1[CH:38]=[C:37]([F:39])[CH:36]=[CH:35][C:34]=1[N:28]1[C:29]2[CH:30]=[C:22]([CH3:21])[CH:23]=[C:24]([NH2:31])[C:25]=2[CH:26]=[N:27]1

참가 물질

4

반응물 3

HCID 1375192,4-Difluoro-1-iodobenzeneHCID 193544286-Methyl-1H-indazol-4-amineHCID 57615925Methyl 3-(4-amino-1H-indazol-1-yl)benzoate

생성물 1

HCID 576159551-(2,4-Difluorophenyl)-6-methyl-1H-indazol-4-amine

실험 절차

Similarly prepared to Intermediate 9 from 6-methyl-1H-indazol-4-amine and 2,4-difluoroiodobenzene.

출처 및 근거

ORD 기록
ord-8876bbe000214efdbc8ef1e8818d0509
출처 데이터셋
uspto-grants-2012_01
특허 번호
US08093281B2

연결된 노트

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