참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | 3-Nitrophthalic anhydride | HCID 21631 | — |
| 반응물 | Bromine | HCID 24408 | — |
| 반응물 | Hydrazine hydrate (1:1) | HCID 24654 | — |
| 반응물 | 3-Aminobenzene-1,2-dicarbohydrazide | HCID 245521 | — |
| 반응물 | 2-Aminophthalohydrazide | HCID 66811964 | — |
| 반응물 | 2-Nitrophthalic hydrazide | HCID 87227270 | — |
| 반응물 | 2-Amino-1,2,3,4-tetrahydrophthalazine-1,4-dione sodium salt dihydrate | HCID 131730842 | — |
| 촉매 | Nickel aluminide | HCID 6336846 | — |
| 생성물 | 2-Amino-1,2,3,4-tetrahydro-1,4-phthalazinedione sodium salt | HCID 66990329 | — |
반응 단계
In the patent RU 2138264, there is described a method for obtaining compound III, that is 2-amino-1,2,3,4-tetrahydrophthalazine-1,4-dione sodium salt dihydrate and it includes transformation of 3-nitrophtalic acid anhydride by means of hydrazine hydrate into 2-nitrophthalic hydrazide which is transformed into 3-aminophthalohydrazide by means of hydrazine hydrate in alkaline medium at presence of nickel-aluminum alloy, thereafter there is performed molecular rearrangement to 2-aminophthalohydrazide by means of bromine under pressure. In the final stage there are mixed 2-amino-phthalohydrazide and NaOH solution at the temperature up to 85° C. thereafter the mixture is filtered and evaporated up to obtaining 2-amino-1,2,3,4-tetrahydro-1,4-phthalazinedione sodium salt dehydrate.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08536171B2 |
|---|
| 출처 데이터셋 | uspto-grants-2013_09 |
|---|
| ORD ID | ord-403c782a2017465b8f1201570a76b30c |
|---|
| 출처 메모 | uspto-grants-2013_09 |
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