2-Methoxy-5-nitro-3-phenylpyridine → 6-Methoxy-5-phenylpyridin-3-amine
반응식
[CH3:1][O:2][C:3]1[C:8]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)=[CH:7][C:6]([N+:15]([O-])=O)=[CH:5][N:4]=1>C(O)C.[Pd]>[CH3:1][O:2][C:3]1[N:4]=[CH:5][C:6]([NH2:15])=[CH:7][C:8]=1[C:9]1[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=1참가 물질
4
실험 절차
A mixture of 2-methoxy-5-nitro-3-phenylpyridine (0.43 mmol, 0.1 g) and Pd/C 10% (0.14 mmol, 0.015 g) in ethanol (2 ml) was stirred for 16 hours under hydrogen atmosphere. The catalyst was filtered off and the solid thoughtfully washed with warm ethanol. The filtrate was evaporated affording 0.085 g (98% of yield) of the expected product.
후처리
- filtrationThe catalyst was filtered off
- washthe solid thoughtfully washed with warm ethanol
- customThe filtrate was evaporated
- customaffording
출처 및 근거
- ORD 기록
- ord-468195bcbf8a4469b45bd7e69b97c2f4
- 출처 데이터셋
- uspto-grants-2013_09
- 특허 번호
- US08536165B2
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