참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | 2-Amino-3-Hydroxypyridine | HCID 28114 | — |
| 반응물 | 5-Aminonicotinic Acid | HCID 354316 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 5-Oxazolo[4,5-b]pyridin-2-yl-pyridin-3-ylamine | HCID 59679866 | — |
반응 단계
In a typical run, 790 mg of 2-amino-3-hydroxypyridine (7.24 mmol) and 1.00 g of 5-aminonicotinic acid (7.24 mmol) were mixed with 10 mL of PPA and stirred at 200° C. for 6 hours. The reaction mixture was cooled to about 100° C. and carefully poured into 100 mL of water. The pH was brought to 6 with solid NaOH and the solids were collected by filtration. After drying under high vacuum, a total of 180 mg of 5-oxazolo [4,5-b]pyridin-2-yl-pyridin-3-ylamine.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08093401B2 |
|---|
| 출처 데이터셋 | uspto-grants-2012_01 |
|---|
| ORD ID | ord-9b1b5b42990f49308ac40a551ecc087d |
|---|
| 출처 메모 | uspto-grants-2012_01 |
|---|
