2,3-Dibromo-5-nitropyridine → 3-Bromo-2-(3-methoxyphenyl)-5-nitropyridine

HRID 41991

반응식

HRID 41991 반응식
Br[C:2]1[C:7]([Br:8])=[CH:6][C:5]([N+:9]([O-:11])=[O:10])=[CH:4][N:3]=1.[CH3:12][O:13][C:14]1[CH:15]=[C:16](B(O)O)[CH:17]=[CH:18][CH:19]=1>>[Br:8][C:7]1[C:2]([C:18]2[CH:17]=[CH:16][CH:15]=[C:14]([O:13][CH3:12])[CH:19]=2)=[N:3][CH:4]=[C:5]([N+:9]([O-:11])=[O:10])[CH:6]=1

참가 물질

3

반응물 2

HCID 12014252,3-Dibromo-5-nitropyridineHCID 2734370(3-Methoxyphenyl)boronic acid

생성물 1

HCID 673943393-Bromo-2-(3-methoxyphenyl)-5-nitropyridine

실험 절차

Obtained (1.15 g, 39% of yield) following the procedure described in Intermediate 2 (step A) starting with 2,3-dibromo-5-nitropyridine (described as Intermediate 5 (step B) (9.33 mmol, 2.630 g) and 3-methoxyphenylboronic acid (9.33 mmol, 1.42 g).

후처리

  1. customObtained
  2. custom(1.15 g, 39% of yield)

출처 및 근거

ORD 기록
ord-717d3c25eed34c5a8d8d7f75c1236cf0
출처 데이터셋
uspto-grants-2013_09
특허 번호
US08536165B2

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