Phenylboronic Acid → 2-(3-Methoxyphenyl)-5-nitro-3-phenylpyridine

HRID 41996노트

반응식

HRID 41996 반응식
Br[C:2]1[C:3]([C:11]2[CH:16]=[CH:15][CH:14]=[C:13]([O:17][CH3:18])[CH:12]=2)=[N:4][CH:5]=[C:6]([N+:8]([O-:10])=[O:9])[CH:7]=1.[C:19]1(B(O)O)[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1>>[CH3:18][O:17][C:13]1[CH:12]=[C:11]([C:3]2[C:2]([C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)=[CH:7][C:6]([N+:8]([O-:10])=[O:9])=[CH:5][N:4]=2)[CH:16]=[CH:15][CH:14]=1

참가 물질

3

반응물 2

HCID 66827Phenylboronic AcidHCID 673943393-Bromo-2-(3-methoxyphenyl)-5-nitropyridine

생성물 1

HCID 673943592-(3-Methoxyphenyl)-5-nitro-3-phenylpyridine수율 87%

실험 절차

Obtained (0.258 g, yield 87%) following the procedure described in Intermediate 27, starting with 3-bromo-2-(3-methoxyphenyl)-5-nitropyridine (0.97 mmol, 0.300 g), phenylboronic acid (1.07 mmol, 0.130 g).

후처리

  1. customObtained (0.258 g, yield 87%)

출처 및 근거

ORD 기록
ord-eef41883aa2f498d8dd582acdb9b6b93
출처 데이터셋
uspto-grants-2013_09
특허 번호
US08536165B2

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