N-(2-acetyl-5-methoxyphenyl)-4-Isopropyl-2-Thiazolecarboxamide → n-(6-Acetyl-3-chloro-4-methoxyphenyl)-4-isopropylthiazole-2-carboxamide
반응식
[CH:1]([C:4]1[N:5]=[C:6]([C:9](Cl)=[O:10])[S:7][CH:8]=1)([CH3:3])[CH3:2].[NH2:12][C:13]1[CH:18]=[C:17]([Cl:19])[C:16]([O:20][CH3:21])=[CH:15][C:14]=1[C:22](=[O:24])[CH3:23].C(C1C=CC(OC)=CC=1NC(C1SC=C(C(C)C)N=1)=O)(=O)C>>[C:22]([C:14]1[C:13]([NH:12][C:9]([C:6]2[S:7][CH:8]=[C:4]([CH:1]([CH3:3])[CH3:2])[N:5]=2)=[O:10])=[CH:18][C:17]([Cl:19])=[C:16]([O:20][CH3:21])[CH:15]=1)(=[O:24])[CH3:23]참가 물질
4
실험 절차
Compound 42g was synthesized from compounds 38 and 40g as a beige solid in 69% yield, according to the procedure as described for compound 42a.
출처 및 근거
- ORD 기록
- ord-3debd0c5580a4c48b612c783e649703d
- 출처 데이터셋
- uspto-grants-2012_01
- 특허 번호
- US08093379B2
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