2,5-Dibromo-4-methylpyridine → 5-Bromo-2-(3-ethoxyphenyl)-4-methylpyridine

HRID 42016노트

반응식

HRID 42016 반응식
Br[C:2]1[CH:7]=[C:6]([CH3:8])[C:5]([Br:9])=[CH:4][N:3]=1.[CH2:10]([O:12][C:13]1[CH:14]=[C:15](B(O)O)[CH:16]=[CH:17][CH:18]=1)[CH3:11]>>[Br:9][C:5]1[C:6]([CH3:8])=[CH:7][C:2]([C:17]2[CH:16]=[CH:15][CH:14]=[C:13]([O:12][CH2:10][CH3:11])[CH:18]=2)=[N:3][CH:4]=1

참가 물질

3

반응물 2

HCID 27344292,5-Dibromo-4-methylpyridineHCID 27739203-Ethoxybenzeneboronic acid

생성물 1

HCID 584158515-Bromo-2-(3-ethoxyphenyl)-4-methylpyridine수율 49%

실험 절차

Obtained (1.14 g, yield 49%) following the procedure described in Intermediate 27, starting with 2,5-dibromo-4-methylpyridine (7.97 mmol, 2.0 g), 3-ethoxyphenylboronic acid (7.97 mmol, 1.32 gl).

후처리

  1. customObtained (1.14 g, yield 49%)

출처 및 근거

ORD 기록
ord-54cf1e9f67bf4effbbc48ebf34145823
출처 데이터셋
uspto-grants-2013_09
특허 번호
US08536165B2

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