1-Acetoxy-2-bromoethane → Ethyl 1-cyclopropyl-4-(2-hydroxyethoxy)-1H-indole-6-carboxylate

HRID 420168노트

반응식

HRID 420168 반응식
[CH:1]1([N:4]2[C:12]3[C:7](=[C:8]([O:18][CH3:19])[CH:9]=[C:10]([C:13]([O:15][CH2:16][CH3:17])=[O:14])[CH:11]=3)[CH:6]=[CH:5]2)[CH2:3][CH2:2]1.[C:20](OCCBr)(=[O:22])C>>[CH:1]1([N:4]2[C:12]3[C:7](=[C:8]([O:18][CH2:19][CH2:20][OH:22])[CH:9]=[C:10]([C:13]([O:15][CH2:16][CH3:17])=[O:14])[CH:11]=3)[CH:6]=[CH:5]2)[CH2:2][CH2:3]1

참가 물질

3

반응물 2

HCID 135641-Acetoxy-2-bromoethaneHCID 66649481ethyl 1-cyclopropyl-4-methoxy-1H-indole-6-carboxylate

생성물 1

HCID 66649692Ethyl 1-cyclopropyl-4-(2-hydroxyethoxy)-1H-indole-6-carboxylate

실험 절차

The compound was prepared according to the procedure for ethyl 1-cyclopropyl-4-methoxy-1H-indole-6-carboxylate but using bromoethyl acetate in place of MeI.

후처리

  1. customThe compound was prepared

출처 및 근거

ORD 기록
ord-e67bbd333ba341009d64675bd5d229aa
출처 데이터셋
uspto-grants-2012_01
특허 번호
US08093389B2

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