2,5-Dibromo-3-methylpyridine → 5-Bromo-2-(3-methoxyphenyl)-3-methylpyridine

HRID 42019

반응식

HRID 42019 반응식
Br[C:2]1[C:7]([CH3:8])=[CH:6][C:5]([Br:9])=[CH:4][N:3]=1.[CH3:10][O:11][C:12]1[CH:13]=[C:14](B(O)O)[CH:15]=[CH:16][CH:17]=1>>[Br:9][C:5]1[CH:6]=[C:7]([CH3:8])[C:2]([C:16]2[CH:15]=[CH:14][CH:13]=[C:12]([O:11][CH3:10])[CH:17]=2)=[N:3][CH:4]=1

참가 물질

3

반응물 2

HCID 8176802,5-Dibromo-3-methylpyridineHCID 2734370(3-Methoxyphenyl)boronic acid

생성물 1

HCID 584157675-Bromo-2-(3-methoxyphenyl)-3-methylpyridine수율 23%

실험 절차

Obtained (1.00 g, yield 23%) following the procedure described in Intermediate 27, starting with 2,5-dibromo-3-methylpyridine (15.94 mmol, 4.0 g), 3-methoxyphenylboronic acid (15.93 mmol, 2.42 g).

후처리

  1. customObtained (1.00 g, yield 23%)

출처 및 근거

ORD 기록
ord-8213884250434fb58cea7573440249ae
출처 데이터셋
uspto-grants-2013_09
특허 번호
US08536165B2

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