2,5-Dibromopyridine → 5-Bromo-2-(2-fluorophenyl)pyridine

HRID 42020

반응식

HRID 42020 반응식
Br[C:2]1[CH:7]=[CH:6][C:5]([Br:8])=[CH:4][N:3]=1.[F:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1B(O)O>>[Br:8][C:5]1[CH:6]=[CH:7][C:2]([C:11]2[CH:12]=[CH:13][CH:14]=[CH:15][C:10]=2[F:9])=[N:3][CH:4]=1

참가 물질

3

반응물 2

HCID 693532,5-DibromopyridineHCID 27343542-Fluorophenylboronic acid

생성물 1

HCID 497585155-Bromo-2-(2-fluorophenyl)pyridine수율 50%

실험 절차

Obtained (0.534 g, yield 50%) following the procedure described in Intermediate 27, starting with 2,5-dibromopyridine (4.22 mmol, 1.0 g), 2-fluorophenylboronic acid (4.22 mmol, 2.42 g).

후처리

  1. customObtained (0.534 g, yield 50%)

출처 및 근거

ORD 기록
ord-7acffb6644024dabb9a6a5f1b9cbe72f
출처 데이터셋
uspto-grants-2013_09
특허 번호
US08536165B2

연결된 노트

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