3-Isopropoxybenzeneboronic acid → 2-(3-Isopropoxyphenyl)-3-methyl-5-nitropyridine

HRID 42027

반응식

HRID 42027 반응식
Br[C:2]1[C:7]([CH3:8])=[CH:6][C:5]([N+:9]([O-:11])=[O:10])=[CH:4][N:3]=1.[CH:12]([O:15][C:16]1[CH:17]=[C:18](B(O)O)[CH:19]=[CH:20][CH:21]=1)([CH3:14])[CH3:13]>>[CH:12]([O:15][C:16]1[CH:21]=[C:20]([C:2]2[C:7]([CH3:8])=[CH:6][C:5]([N+:9]([O-:11])=[O:10])=[CH:4][N:3]=2)[CH:19]=[CH:18][CH:17]=1)([CH3:14])[CH3:13]

참가 물질

3

반응물 2

HCID 50839323-Isopropoxybenzeneboronic acidHCID 52004662-Bromo-3-methyl-5-nitropyridine

생성물 1

HCID 673943532-(3-Isopropoxyphenyl)-3-methyl-5-nitropyridine수율 82%

실험 절차

Obtained (1.03 g, yield 82%) following the procedure described in Intermediate 27, starting with 2-bromo-3-methyl-5-nitropyridine (4.61 mmol, 1.0 g), 3-isopropoxyphenylboronic acid (4.61 mmol, 0.83 g).

후처리

  1. customObtained (1.03 g, yield 82%)

출처 및 근거

ORD 기록
ord-48cfa2efc1374cb09f4ba93e963a43a4
출처 데이터셋
uspto-grants-2013_09
특허 번호
US08536165B2

연결된 노트

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