(3-Carbamoylphenyl)boronic acid → 3-(3-Methyl-5-nitropyridin-2-yl)benzamide

HRID 42028

반응식

HRID 42028 반응식
Br[C:2]1[C:7]([CH3:8])=[CH:6][C:5]([N+:9]([O-:11])=[O:10])=[CH:4][N:3]=1.[C:12]([C:15]1[CH:16]=[C:17](B(O)O)[CH:18]=[CH:19][CH:20]=1)(=[O:14])[NH2:13]>>[CH3:8][C:7]1[C:2]([C:19]2[CH:20]=[C:15]([CH:16]=[CH:17][CH:18]=2)[C:12]([NH2:13])=[O:14])=[N:3][CH:4]=[C:5]([N+:9]([O-:11])=[O:10])[CH:6]=1

참가 물질

3

반응물 2

HCID 2737814(3-Carbamoylphenyl)boronic acidHCID 52004662-Bromo-3-methyl-5-nitropyridine

생성물 1

HCID 673941663-(3-Methyl-5-nitropyridin-2-yl)benzamide수율 95%

실험 절차

Obtained (0.225 g, yield 95%) following the procedure described in Intermediate 27, starting with 2-bromo-3-methyl-5-nitropyridine (0.92 mmol, 0.200 g), 3-carbamoylphenyl boronic acid (0.92 mmol, 0.152 g).

후처리

  1. customObtained (0.225 g, yield 95%)

출처 및 근거

ORD 기록
ord-7f080017fac3419a8fc81fdf3499b97c
출처 데이터셋
uspto-grants-2013_09
특허 번호
US08536165B2

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