Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Amino-6-chloro-4-picoline → 6-(2-Fluoro-5-methoxyphenyl)-4-methylpyridin-3-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Amino-6-chloro-4-picoline | HCID 2734425 | — |
| 반응물 | 2-Fluoro-5-methoxyphenylboronic acid | HCID 4157211 | — |
| 생성물 | 6-(2-Fluoro-5-methoxyphenyl)-4-methylpyridin-3-amine | HCID 58415871 | 76% |
반응 단계
Obtained (1.225 g, yield 76%) following the procedure described in Intermediate 27, starting with 6-chloro-4-methylpyridin-3-amine (7.01 mmol, 1.000 g), 2-fluoro-5-methoxyphenylboronic acid (7.01 mmol, 1.191 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08536165B2 |
| 출처 데이터셋 | uspto-grants-2013_09 |
| ORD ID | ord-1326f287e68d439b9f2ecc60f9cc5155 |
| 출처 메모 | uspto-grants-2013_09 |