(3-Methoxyphenyl)boronic acid → 2-(3-Methoxyphenyl)-3-methyl-5-nitropyridine

HRID 42031

반응식

HRID 42031 반응식
Br[C:2]1[C:7]([CH3:8])=[CH:6][C:5]([N+:9]([O-:11])=[O:10])=[CH:4][N:3]=1.[CH3:12][O:13][C:14]1[CH:15]=[C:16](B(O)O)[CH:17]=[CH:18][CH:19]=1>>[CH3:12][O:13][C:14]1[CH:19]=[C:18]([C:2]2[C:7]([CH3:8])=[CH:6][C:5]([N+:9]([O-:11])=[O:10])=[CH:4][N:3]=2)[CH:17]=[CH:16][CH:15]=1

참가 물질

3

반응물 2

HCID 2734370(3-Methoxyphenyl)boronic acidHCID 52004662-Bromo-3-methyl-5-nitropyridine

생성물 1

HCID 673941622-(3-Methoxyphenyl)-3-methyl-5-nitropyridine수율 72%

실험 절차

Obtained (2.43 g, yield 72%) following the procedure described in Intermediate 27, starting with 2-bromo-3-methyl-5-nitropyridine (13.82 mmol, 3.0 g), 3-methoxyphenylboronic acid (13.82 mmol, 2.10 g).

후처리

  1. customObtained (2.43 g, yield 72%)

출처 및 근거

ORD 기록
ord-92a63ddccc2b42dfbab22f3eabf0d2ee
출처 데이터셋
uspto-grants-2013_09
특허 번호
US08536165B2

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