6-Bromopyridin-3-amine → 6-(2-(Trifluoromethyl)phenyl)pyridin-3-amine

HRID 42034

반응식

HRID 42034 반응식
Br[C:2]1[N:7]=[CH:6][C:5]([NH2:8])=[CH:4][CH:3]=1.[F:9][C:10]([F:21])([F:20])[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=1B(O)O>>[F:9][C:10]([F:21])([F:20])[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=1[C:2]1[N:7]=[CH:6][C:5]([NH2:8])=[CH:4][CH:3]=1

참가 물질

3

반응물 2

HCID 6428116-Bromopyridin-3-amineHCID 27343872-(Trifluoromethyl)benzeneboronic acid

생성물 1

HCID 665212636-(2-(Trifluoromethyl)phenyl)pyridin-3-amine수율 59%

실험 절차

Obtained (2.05 g, yield 59%) following the procedure described in Intermediate 27, starting with 6-bromopyridin-3-amine, 2-(trifluoromethyl)phenylboronic acid.

후처리

  1. customObtained (2.05 g, yield 59%)

출처 및 근거

ORD 기록
ord-ffd306596ef8463987e9e68d2ef78b8c
출처 데이터셋
uspto-grants-2013_09
특허 번호
US08536165B2

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