2,5-Dichlorobenzoic acid → 2-(6-Bromo-5-methylpyridin-3-ylamino)-5-chlorobenzoic acid

HRID 42044

반응식

HRID 42044 반응식
[Br:1][C:2]1[N:7]=[CH:6][C:5]([NH2:8])=[CH:4][C:3]=1[CH3:9].Cl[C:11]1[CH:19]=[CH:18][C:17]([Cl:20])=[CH:16][C:12]=1[C:13]([OH:15])=[O:14]>>[Br:1][C:2]1[N:7]=[CH:6][C:5]([NH:8][C:11]2[CH:19]=[CH:18][C:17]([Cl:20])=[CH:16][C:12]=2[C:13]([OH:15])=[O:14])=[CH:4][C:3]=1[CH3:9]

참가 물질

3

반응물 2

HCID 57842,5-Dichlorobenzoic acidHCID 123624465-Amino-2-bromo-3-methylpyridine

생성물 1

HCID 866572602-(6-Bromo-5-methylpyridin-3-ylamino)-5-chlorobenzoic acid수율 24%

실험 절차

Obtained (0.51 g, yield 24%) following the procedure described in Intermediate 13 starting with 6-bromo-5-methylpyridin-3-amine (5.35 mmol, 1.0 g) and 2,5-dichlorobenzoic acid (10.68 mmol, 2.04 g).

후처리

  1. customObtained (0.51 g, yield 24%)

출처 및 근거

ORD 기록
ord-c1621bb7fc9d48d491d4c64871edc448
출처 데이터셋
uspto-grants-2013_09
특허 번호
US08536165B2

연결된 노트

불러오는 중…