Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methanol → Methyl 2-chloro-4-methylbenzoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methanol | HCID 887 | — |
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 반응물 | 2-Chloro-4-methylbenzoic acid | HCID 2735755 | — |
| 생성물 | Methyl 2-chloro-4-methylbenzoate | HCID 22019481 | — |
반응 단계
2-chloro-4-methylbenzoic acid (500 mg, 2.93 mmol) was dissolved in Methanol (7 mL) and SOCl2 (0.215 mL, 2.93 mmol) was slowly added to the mixture and the reaction was left at room temperature overnight. Next morning HPLC showed completion. Volatiles were removed under vacuum to afford 526 mg of the title compound as brown oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08097628B2 |
| 출처 데이터셋 | uspto-grants-2012_01 |
| ORD ID | ord-816d5ce1e99a4848bd036311ac824933 |
| 출처 메모 | uspto-grants-2012_01 |