5-Iodosalicylic acid → N-[3,5-bis(trifluoromethyl)phenyl]-2-hydroxy-5-iodo-benzamide

HRID 421040

반응식

HRID 421040 반응식
[I:1][C:2]1[CH:10]=[C:6]([C:7]([OH:9])=O)[C:5]([OH:11])=[CH:4][CH:3]=1.[F:12][C:13]([F:26])([F:25])[C:14]1[CH:15]=[C:16]([CH:18]=[C:19]([C:21]([F:24])([F:23])[F:22])[CH:20]=1)[NH2:17]>>[F:12][C:13]([F:25])([F:26])[C:14]1[CH:15]=[C:16]([NH:17][C:7](=[O:9])[C:6]2[CH:10]=[C:2]([I:1])[CH:3]=[CH:4][C:5]=2[OH:11])[CH:18]=[C:19]([C:21]([F:22])([F:24])[F:23])[CH:20]=1

참가 물질

3

반응물 2

HCID 83885-Iodosalicylic acidHCID 9480Benzenamine, 3,5-bis(trifluoromethyl)-

생성물 1

HCID 11190699N-[3,5-bis(trifluoromethyl)phenyl]-2-hydroxy-5-iodo-benzamide수율 62.2%

실험 절차

Using 5-iodosalicylic acid and 3,5-bis(trifluoromethyl)aniline as the raw materials, the same operation as the example 16 gave the title compound.

출처 및 근거

ORD 기록
ord-c73db785fcaa442d84a9fcf109ef49d6
출처 데이터셋
uspto-grants-2012_01
특허 번호
US08097759B2

연결된 노트

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