Benzenamine, 3,5-bis(trifluoromethyl)- → N-[3,5-bis(trifluoromethyl)phenyl]-2-hydroxy-5-methoxy-benzamide

HRID 421068

반응식

HRID 421068 반응식
[CH3:1][O:2][C:3]1[CH:11]=[C:7]([C:8]([OH:10])=O)[C:6]([OH:12])=[CH:5][CH:4]=1.[F:13][C:14]([F:27])([F:26])[C:15]1[CH:16]=[C:17]([CH:19]=[C:20]([C:22]([F:25])([F:24])[F:23])[CH:21]=1)[NH2:18]>>[F:13][C:14]([F:26])([F:27])[C:15]1[CH:16]=[C:17]([NH:18][C:8](=[O:10])[C:7]2[CH:11]=[C:3]([O:2][CH3:1])[CH:4]=[CH:5][C:6]=2[OH:12])[CH:19]=[C:20]([C:22]([F:23])([F:25])[F:24])[CH:21]=1

참가 물질

3

반응물 2

HCID 9480Benzenamine, 3,5-bis(trifluoromethyl)-HCID 757875-Methoxysalicylic Acid

생성물 1

HCID 11314966N-[3,5-bis(trifluoromethyl)phenyl]-2-hydroxy-5-methoxy-benzamide수율 56.8%

실험 절차

Using 5-methoxysalicylic acid and 3,5-bis(trifluoromethyl)aniline as the raw materials, the same operation as the example 16 gave the title compound.

출처 및 근거

ORD 기록
ord-ebea10264f5a47c9b129907467322caf
출처 데이터셋
uspto-grants-2012_01
특허 번호
US08097759B2

연결된 노트

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