5-Chlorosalicylic Acid → 5-Chloro-2-hydroxy-N-[4-methoxy-3-(trifluoromethyl)phenyl]benzamide

HRID 421107

반응식

HRID 421107 반응식
[Cl:1][C:2]1[CH:10]=[C:6]([C:7]([OH:9])=O)[C:5]([OH:11])=[CH:4][CH:3]=1.[CH3:12][O:13][C:14]1[CH:20]=[CH:19][C:17]([NH2:18])=[CH:16][C:15]=1[C:21]([F:24])([F:23])[F:22]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([OH:11])=[C:6]([CH:10]=1)[C:7]([NH:18][C:17]1[CH:19]=[CH:20][C:14]([O:13][CH3:12])=[C:15]([C:21]([F:22])([F:23])[F:24])[CH:16]=1)=[O:9]

참가 물질

3

반응물 2

HCID 94475-Chlorosalicylic AcidHCID 6007055-Amino-2-methoxybenzotrifluoride

생성물 1

HCID 178601055-Chloro-2-hydroxy-N-[4-methoxy-3-(trifluoromethyl)phenyl]benzamide수율 79.1%

실험 절차

Using 5-chlorosalicylic acid and 4-methoxy-3-(trifluoromethyl)aniline as the raw materials, the same operation as the example 16 gave the title compound.

출처 및 근거

ORD 기록
ord-bceb10fb3ae24ad7bbf923f1638743cc
출처 데이터셋
uspto-grants-2012_01
특허 번호
US08097759B2

연결된 노트

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