5-Bromosalicylic acid → 5-Bromo-N-[2-chloro-4-(trifluoromethyl)phenyl]-2-hydroxybenzamide

HRID 421113

반응식

HRID 421113 반응식
[Br:1][C:2]1[CH:10]=[C:6]([C:7]([OH:9])=O)[C:5]([OH:11])=[CH:4][CH:3]=1.[Cl:12][C:13]1[CH:19]=[C:18]([C:20]([F:23])([F:22])[F:21])[CH:17]=[CH:16][C:14]=1[NH2:15]>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([OH:11])=[C:6]([CH:10]=1)[C:7]([NH:15][C:14]1[CH:16]=[CH:17][C:18]([C:20]([F:21])([F:22])[F:23])=[CH:19][C:13]=1[Cl:12])=[O:9]

참가 물질

3

반응물 2

HCID 69725-Bromosalicylic acidHCID 1620012-Chloro-4-trifluoromethylaniline

생성물 1

HCID 178602905-Bromo-N-[2-chloro-4-(trifluoromethyl)phenyl]-2-hydroxybenzamide수율 34.9%

실험 절차

Using 5-bromosalicylic acid and 2-chloro-4-(trifluoromethyl)aniline as the raw materials, the same operation as the example 16 gave the title compound.

출처 및 근거

ORD 기록
ord-752ab556dff24b95aaf3f20eaa2c0335
출처 데이터셋
uspto-grants-2012_01
특허 번호
US08097759B2

연결된 노트

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