5-Methylsalicylic acid → 2-Hydroxy-5 methyl-N-[4-methyl-3-(trifluoromethyl)phenyl]benzamide

HRID 421118

반응식

HRID 421118 반응식
[CH3:1][C:2]1[CH:10]=[C:6]([C:7]([OH:9])=O)[C:5]([OH:11])=[CH:4][CH:3]=1.[CH3:12][C:13]1[CH:19]=[CH:18][C:16]([NH2:17])=[CH:15][C:14]=1[C:20]([F:23])([F:22])[F:21]>>[OH:11][C:5]1[CH:4]=[CH:3][C:2]([CH3:1])=[CH:10][C:6]=1[C:7]([NH:17][C:16]1[CH:18]=[CH:19][C:13]([CH3:12])=[C:14]([C:20]([F:21])([F:22])[F:23])[CH:15]=1)=[O:9]

참가 물질

3

반응물 2

HCID 69735-Methylsalicylic acidHCID 27377154-Methyl-3-(trifluoromethyl)aniline

생성물 1

HCID 178602532-Hydroxy-5 methyl-N-[4-methyl-3-(trifluoromethyl)phenyl]benzamide수율 63.7%

실험 절차

Using 5-methylsalicylic acid and 4-methyl-3-(trifluoromethyl)aniline as the raw materials, the same operation as the example 16 gave the title compound.

출처 및 근거

ORD 기록
ord-be85630104924156bd0054662083430e
출처 데이터셋
uspto-grants-2012_01
특허 번호
US08097759B2

연결된 노트

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