Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dichloromethane → 2-(Chloromethyl)-1-methylbenzimidazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dichloromethane | HCID 6344 | — |
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 반응물 | (1-methyl-1H-1,3-benzodiazol-2-yl)methanol | HCID 344177 | — |
| 생성물 | 2-(Chloromethyl)-1-methylbenzimidazole | HCID 248044 | — |
반응 단계
A solution of (1-methyl-1H-benzoimidazol-2-yl)-methanol (500 mg, 3.08 mmol) and SOCl2 (1.1 mL) in DCM (2 mmol) was stirred at room temperature for 3 hours. After evaporation of the solvents, 2-chloromethyl-1-methyl-1H-benzoimidazole (556 mg, 3.08 mmol) was obtained and was used without any purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08101637B2 |
| 출처 데이터셋 | uspto-grants-2012_01 |
| ORD ID | ord-0b66e1b3149f47a1bf2af31c1d742596 |
| 출처 메모 | uspto-grants-2012_01 |