5-ethyl-6-nitro-2,3-dihydro-1H-indole → 5-ethyl-6-nitro-1H-indole
반응식
[CH2:1]([C:3]1[CH:4]=[C:5]2[C:9](=[CH:10][C:11]=1[N+:12]([O-:14])=[O:13])[NH:8][CH2:7][CH2:6]2)[CH3:2]>C(Cl)Cl.O=[Mn]=O>[CH2:1]([C:3]1[CH:4]=[C:5]2[C:9](=[CH:10][C:11]=1[N+:12]([O-:14])=[O:13])[NH:8][CH:7]=[CH:6]2)[CH3:2]참가 물질
4
실험 절차
To a solution of 5-ethyl-6-nitro-2,3-dihydro-1H-indole (1.9 g, 9.9 mmol) in CH2Cl2 (30 mL) was added MnO2 (4 g, 46 mmol). The mixture was stirred at room temperature for 8 h. The solid was filtered off and the filtrate was concentrated to dryness to give crude 5-ethyl-6-nitro-1H-indole (1.9 g, quant.).
후처리
- filtrationThe solid was filtered off
- concentrationthe filtrate was concentrated to dryness
출처 및 근거
- ORD 기록
- ord-41da9e2492494e2a9e5e092007e20e4c
- 출처 데이터셋
- uspto-grants-2012_01
- 특허 번호
- US08101767B2
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