Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Bromine → 1-(5-bromo-2,3-dihydro-1H-indol-1-yl)ethan-1-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Bromine | HCID 24408 | — |
| 반응물 | 1-(2,3-Dihydro-1H-indol-1-yl)ethan-1-one | HCID 27673 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 생성물 | 1-(5-bromo-2,3-dihydro-1H-indol-1-yl)ethan-1-one | HCID 721847 | 115.7% |
반응 단계
To a solution of 1-(2,3-dihydro-indol-1-yl)-ethanone (58.0 g, 0.36 mol) in acetic acid (3000 mL) was added Br2 (87.0 g, 0.54 mol) at 10° C. The mixture was stirred at room temperature for 4 h. The precipitate was collected via filtration to give crude 1-(5-bromo-2,3-dihydro-indol-1-yl)-ethanone (100 g, 96%), which was used directly in the next step.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08101767B2 |
| 출처 데이터셋 | uspto-grants-2012_01 |
| ORD ID | ord-e253824903304cc0a7ee3e2745e780c3 |
| 출처 메모 | uspto-grants-2012_01 |