참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 1,2-Dichloroethane | HCID 11 | — |
| 반응물 | 6-Bromohexanoic acid | HCID 20210 | — |
| 반응물 | 2-Hydroxypropyl acrylate | HCID 61249 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 2-[(6-Bromohexanoyl)oxy]propyl acrylate | HCID 59005029 | — |
반응 단계
To a 0° C. cooled mixture of 6-bromohexanoic acid (9.89 g), 2-hydroxypropyl acrylate (6 g), in CH2Cl2 (30 ml), EDC (7.89 g) was added. After being stirred for 30 min the reaction mixture was diluted with additional 20 ml of CH2Cl2 and stirring was continued for 16 h at room temperature. It was then filtered over celite and the filtrate was evaporated to dryness. The obtained beige-yellow residue was purified by silica column chromatography to give nearly pure material as transparent oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08105662B2 |
|---|
| 출처 데이터셋 | uspto-grants-2012_01 |
|---|
| ORD ID | ord-0e5407f232de4411a3a215497f6e7f7d |
|---|
| 출처 메모 | uspto-grants-2012_01 |
|---|
